HCSGD entry for FLAD1
1. General information
| Official gene symbol | FLAD1 |
|---|---|
| Entrez ID | 80308 |
| Gene full name | flavin adenine dinucleotide synthetase 1 |
| Other gene symbols | FAD1 FADS RP11-307C12.7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0003919 | FMN adenylyltransferase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005759 | Mitochondrial matrix | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006747 | FAD biosynthetic process | IEA | biological_process |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0006771 | Riboflavin metabolic process | TAS | biological_process |
| GO:0006777 | Mo-molybdopterin cofactor biosynthetic process | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1575437217 | 0.6486567722 | 0.7879303778 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6809906192 |
| GSE13712_SHEAR | Up | 0.1779623706 |
| GSE13712_STATIC | Up | 0.3741404829 |
| GSE19018 | Down | -0.2866958137 |
| GSE19899_A1 | Up | 0.0881890485 |
| GSE19899_A2 | Up | 0.4217277764 |
| PubMed_21979375_A1 | Up | 0.4450139409 |
| PubMed_21979375_A2 | Up | 0.4599138588 |
| GSE35957 | Down | -0.0370148404 |
| GSE36640 | Up | 0.0687159630 |
| GSE54402 | Up | 0.4360206827 |
| GSE9593 | Down | -0.2035484930 |
| GSE43922 | Up | 0.3198176178 |
| GSE24585 | Down | -0.3345593064 |
| GSE37065 | Down | -0.0493366020 |
| GSE28863_A1 | Down | -0.3010595054 |
| GSE28863_A2 | Down | -0.1437741405 |
| GSE28863_A3 | Down | -0.0237747125 |
| GSE28863_A4 | Down | -0.1679211368 |
| GSE48662 | Down | -0.0460716219 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027748 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032427 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032427 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037007 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044739 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
