HCSGD entry for MED28
1. General information
| Official gene symbol | MED28 |
|---|---|
| Entrez ID | 80306 |
| Gene full name | mediator complex subunit 28 |
| Other gene symbols | 1500003D12Rik EG1 magicin |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016592 | Mediator complex | IEA | cellular_component |
| GO:0019827 | Stem cell maintenance | IEA | biological_process |
| GO:0030864 | Cortical actin cytoskeleton | IEA | cellular_component |
| GO:0051151 | Negative regulation of smooth muscle cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9429233160 | 0.1301435052 | 0.9999902473 | 0.6942657479 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0859325119 |
| GSE13712_SHEAR | Down | -0.3281234923 |
| GSE13712_STATIC | Down | -0.4292414125 |
| GSE19018 | Down | -0.2555817700 |
| GSE19899_A1 | Up | 0.0127810674 |
| GSE19899_A2 | Down | -0.0322103690 |
| PubMed_21979375_A1 | Up | 0.1011762607 |
| PubMed_21979375_A2 | Down | -0.2288684489 |
| GSE35957 | Up | 0.0381255288 |
| GSE36640 | Down | -0.4778506435 |
| GSE54402 | Up | 0.2754991112 |
| GSE9593 | Down | -0.0834876620 |
| GSE43922 | Up | 0.0048735281 |
| GSE24585 | Up | 0.0339276759 |
| GSE37065 | Down | -0.1148052138 |
| GSE28863_A1 | Up | 0.2130090910 |
| GSE28863_A2 | Up | 0.1476293993 |
| GSE28863_A3 | Down | -0.6175856418 |
| GSE28863_A4 | Down | -0.3160021755 |
| GSE48662 | Up | 0.0740388499 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | MIRT002554 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037505 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038176 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30d-5p | MIMAT0000245 | MIRT047827 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052202 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | NA | hsa-miR-373 | 15685193 | |||
| hsa-let-7a-5p | MIMAT0000062 | NA | hsa-let-7a | 19939273 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
