HCSGD entry for MLLT10
1. General information
| Official gene symbol | MLLT10 |
|---|---|
| Entrez ID | 8028 |
| Gene full name | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| Other gene symbols | AF10 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9482001444 | 0.1205739220 | 0.9999902473 | 0.6671486651 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1124805249 |
| GSE13712_SHEAR | Up | 0.0812658538 |
| GSE13712_STATIC | Up | 0.0112825096 |
| GSE19018 | Down | -0.0709285189 |
| GSE19899_A1 | Down | -0.0822877485 |
| GSE19899_A2 | Down | -0.3492610599 |
| PubMed_21979375_A1 | Down | -0.5067787242 |
| PubMed_21979375_A2 | Down | -0.5354998775 |
| GSE35957 | Down | -0.2833051072 |
| GSE36640 | Down | -0.6397276616 |
| GSE54402 | Down | -0.1154904983 |
| GSE9593 | Up | 0.0297084095 |
| GSE43922 | Down | -0.0402253712 |
| GSE24585 | Up | 0.1677558643 |
| GSE37065 | Down | -0.0135891805 |
| GSE28863_A1 | Up | 0.3842195200 |
| GSE28863_A2 | Up | 0.0917974281 |
| GSE28863_A3 | Down | -0.3368921322 |
| GSE28863_A4 | Up | 0.0720414357 |
| GSE48662 | Down | -0.4074856140 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-132-3p | MIMAT0000426 | MIRT021746 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
