HCSGD entry for GRPEL1


1. General information

Official gene symbolGRPEL1
Entrez ID80273
Gene full nameGrpE-like 1, mitochondrial (E. coli)
Other gene symbolsHMGE
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000774Adenyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005739MitochondrionIDAcellular_component
GO:0005759Mitochondrial matrixIDAcellular_component
GO:0006457Protein foldingIEAbiological_process
GO:0006626Protein targeting to mitochondrionTASbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0051082Unfolded protein bindingIDAmolecular_function
GO:0051087Chaperone bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01456525210.73391043270.29974354961.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0419565704
GSE13712_SHEARUp0.4967831920
GSE13712_STATICUp0.2748129649
GSE19018Up0.0216818172
GSE19899_A1Up1.0058988109
GSE19899_A2Up1.2993433993
PubMed_21979375_A1Up1.7065409463
PubMed_21979375_A2Up0.7952489241
GSE35957Down-0.3703458686
GSE36640Up0.0465257759
GSE54402Up1.1040257122
GSE9593Down-0.2299668819
GSE43922Up0.6537129385
GSE24585Down-0.3988886819
GSE37065Up0.0253880202
GSE28863_A1Down-0.4927474655
GSE28863_A2Down-0.1049697392
GSE28863_A3Down-0.0412285423
GSE28863_A4Down-0.0476314945
GSE48662Down-0.0122824329

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020623ProteomicsFunctional MTI (Weak)18668040
hsa-miR-98-5pMIMAT0000096MIRT027433MicroarrayFunctional MTI (Weak)19088304
hsa-miR-652-3pMIMAT0003322MIRT039522CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT042368CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.