HCSGD entry for ITPKC
1. General information
| Official gene symbol | ITPKC |
|---|---|
| Entrez ID | 80271 |
| Gene full name | inositol-trisphosphate 3-kinase C |
| Other gene symbols | IP3-3KC IP3KC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0008440 | Inositol-1,4,5-trisphosphate 3-kinase activity | IEA | molecular_function |
| GO:0043647 | Inositol phosphate metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0222591163 | 0.9632721515 | 0.3570275442 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2728140111 |
| GSE13712_SHEAR | Up | 0.5928513385 |
| GSE13712_STATIC | Up | 0.3471597639 |
| GSE19018 | Down | -0.0413296785 |
| GSE19899_A1 | Up | 0.1880296442 |
| GSE19899_A2 | Up | 0.2855921485 |
| PubMed_21979375_A1 | Up | 0.5183742269 |
| PubMed_21979375_A2 | Up | 0.9972992783 |
| GSE35957 | Up | 0.0968802312 |
| GSE36640 | Up | 0.6823660196 |
| GSE54402 | Up | 0.2097783605 |
| GSE9593 | Up | 0.5718783791 |
| GSE43922 | Up | 0.1966547236 |
| GSE24585 | Down | -0.3101811104 |
| GSE37065 | Down | -0.1033523804 |
| GSE28863_A1 | Up | 0.1172072362 |
| GSE28863_A2 | Down | -0.1049330804 |
| GSE28863_A3 | Up | 0.1816324739 |
| GSE28863_A4 | Up | 0.0762224961 |
| GSE48662 | Up | 0.4250926736 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050413 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
