HCSGD entry for NUP214


1. General information

Official gene symbolNUP214
Entrez ID8021
Gene full namenucleoporin 214kDa
Other gene symbolsCAIN CAN D9S46E N214
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleTASbiological_process
GO:0005215Transporter activityTASmolecular_function
GO:0005487Nucleocytoplasmic transporter activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005643Nuclear poreIEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006406MRNA export from nucleusIEAbiological_process
GO:0006606Protein import into nucleusIEAbiological_process
GO:0006611Protein export from nucleusIMPbiological_process
GO:0007077Mitotic nuclear envelope disassemblyTASbiological_process
GO:0008645Hexose transportTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0010827Regulation of glucose transportTASbiological_process
GO:0015758Glucose transportTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0051726Regulation of cell cycleIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72014869880.34791681170.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0906927828
GSE13712_SHEARDown-0.1672290412
GSE13712_STATICDown-0.2238613093
GSE19018Down-0.0777412207
GSE19899_A1Down-0.0850300637
GSE19899_A2Down-0.3102023888
PubMed_21979375_A1Up0.1171519939
PubMed_21979375_A2Down-0.0141136464
GSE35957Down-0.1276001152
GSE36640Down-0.4489699254
GSE54402Down-0.0172641027
GSE9593Down-0.1547264163
GSE43922Down-0.0179485350
GSE24585Up0.0281089235
GSE37065Down-0.0120998147
GSE28863_A1Up0.8767587097
GSE28863_A2Up0.5103973731
GSE28863_A3Down-0.1863252608
GSE28863_A4Up0.0833111520
GSE48662Up0.0694018405

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7b-5pMIMAT0000063MIRT032370ProteomicsFunctional MTI (Weak)18668040
hsa-let-7b-5pMIMAT0000063MIRT032370CLASHFunctional MTI (Weak)23622248
hsa-miR-193b-3pMIMAT0002819MIRT041295CLASHFunctional MTI (Weak)23622248
hsa-miR-331-3pMIMAT0000760MIRT043374CLASHFunctional MTI (Weak)23622248
hsa-miR-328-3pMIMAT0000752MIRT043751CLASHFunctional MTI (Weak)23622248
hsa-miR-149-5pMIMAT0000450MIRT045641CLASHFunctional MTI (Weak)23622248
hsa-miR-15b-5pMIMAT0000417MIRT046465CLASHFunctional MTI (Weak)23622248
hsa-miR-22-3pMIMAT0000077MIRT050464CLASHFunctional MTI (Weak)23622248
hsa-miR-20a-5pMIMAT0000075MIRT050542CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.