HCSGD entry for OPA3
1. General information
| Official gene symbol | OPA3 |
|---|---|
| Entrez ID | 80207 |
| Gene full name | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| Other gene symbols | MGA3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | IDA NAS | cellular_component |
| GO:0007601 | Visual perception | IMP | biological_process |
| GO:0019216 | Regulation of lipid metabolic process | IEA | biological_process |
| GO:0040007 | Growth | IEA | biological_process |
| GO:0050896 | Response to stimulus | IEA | biological_process |
| GO:0050905 | Neuromuscular process | IEA | biological_process |
| GO:0070584 | Mitochondrion morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2841089282 | 0.9314600547 | 0.9830883064 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0952120075 |
| GSE13712_SHEAR | Down | -0.0337329109 |
| GSE13712_STATIC | Up | 0.0113437053 |
| GSE19018 | Down | -0.1270603281 |
| GSE19899_A1 | Up | 0.0609822951 |
| GSE19899_A2 | Up | 0.5696797435 |
| PubMed_21979375_A1 | Up | 0.6176942644 |
| PubMed_21979375_A2 | Up | 0.2115678366 |
| GSE35957 | Up | 0.0157614978 |
| GSE36640 | Up | 0.1115474967 |
| GSE54402 | Up | 0.2705845225 |
| GSE9593 | Up | 0.2179942846 |
| GSE43922 | Up | 0.0837876033 |
| GSE24585 | Down | -0.1762336690 |
| GSE37065 | Up | 0.0952255164 |
| GSE28863_A1 | Up | 0.0407421880 |
| GSE28863_A2 | Down | -0.0180157360 |
| GSE28863_A3 | Down | -0.1858808988 |
| GSE28863_A4 | Up | 0.0597225208 |
| GSE48662 | Down | -0.0978592966 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036292 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041812 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-3615 | MIMAT0017994 | MIRT052849 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
