HCSGD entry for FBXO11
1. General information
| Official gene symbol | FBXO11 |
|---|---|
| Entrez ID | 80204 |
| Gene full name | F-box protein 11 |
| Other gene symbols | FBX11 PRMT9 UBR6 VIT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000151 | Ubiquitin ligase complex | NAS | cellular_component |
| GO:0004842 | Ubiquitin-protein ligase activity | IEA NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005694 | Chromosome | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006464 | Cellular protein modification process | IDA | biological_process |
| GO:0006479 | Protein methylation | IDA | biological_process |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | NAS | biological_process |
| GO:0007605 | Sensory perception of sound | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016274 | Protein-arginine N-methyltransferase activity | IDA | molecular_function |
| GO:0016567 | Protein ubiquitination | NAS | biological_process |
| GO:0032259 | Methylation | IDA | biological_process |
| GO:0035246 | Peptidyl-arginine N-methylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7195852361 | 0.0454066411 | 0.9999902473 | 0.4003618553 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4137674626 |
| GSE13712_SHEAR | Up | 0.0660458124 |
| GSE13712_STATIC | Up | 0.0838885854 |
| GSE19018 | Down | -0.0815417036 |
| GSE19899_A1 | Down | -0.2104185980 |
| GSE19899_A2 | Down | -0.4154317516 |
| PubMed_21979375_A1 | Down | -0.4066161005 |
| PubMed_21979375_A2 | Down | -0.9101677609 |
| GSE35957 | Down | -0.0550851592 |
| GSE36640 | Down | -0.7504148706 |
| GSE54402 | Down | -0.0527985638 |
| GSE9593 | Down | -0.2038057514 |
| GSE43922 | Down | -0.2416408432 |
| GSE24585 | Down | -0.1455441695 |
| GSE37065 | Down | -0.0133420686 |
| GSE28863_A1 | Up | 0.8336639147 |
| GSE28863_A2 | Up | 1.0717628185 |
| GSE28863_A3 | Down | -0.2322965384 |
| GSE28863_A4 | Down | -0.3651974580 |
| GSE48662 | Up | 0.3906884217 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025191 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027332 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030357 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT031059 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-421 | MIMAT0003339 | MIRT039392 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
