HCSGD entry for HKDC1
1. General information
| Official gene symbol | HKDC1 |
|---|---|
| Entrez ID | 80201 |
| Gene full name | hexokinase domain containing 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001678 | Cellular glucose homeostasis | IBA | biological_process |
| GO:0004340 | Glucokinase activity | IBA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005829 | Cytosol | IBA | cellular_component |
| GO:0006096 | Glycolysis | IBA | biological_process |
| GO:0008865 | Fructokinase activity | IBA | molecular_function |
| GO:0019158 | Mannokinase activity | IBA | molecular_function |
| GO:0046835 | Carbohydrate phosphorylation | IBA | biological_process |
| GO:0051156 | Glucose 6-phosphate metabolic process | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7615678014 | 0.8350130694 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0704754481 |
| GSE13712_SHEAR | Up | 0.1335725350 |
| GSE13712_STATIC | Down | -0.0345387317 |
| GSE19018 | Up | 0.0987941307 |
| GSE19899_A1 | Up | 0.0932946105 |
| GSE19899_A2 | Down | -0.0053327783 |
| PubMed_21979375_A1 | Down | -0.1709548996 |
| PubMed_21979375_A2 | Down | -0.1196482167 |
| GSE35957 | Down | -0.0347217719 |
| GSE36640 | Up | 0.1120279531 |
| GSE54402 | Up | 0.1209940601 |
| GSE9593 | Down | -0.0698632467 |
| GSE43922 | Up | 0.0257082898 |
| GSE24585 | Down | -0.1437556907 |
| GSE37065 | Down | -0.0318671750 |
| GSE28863_A1 | Down | -0.1297287094 |
| GSE28863_A2 | Down | -0.0258233190 |
| GSE28863_A3 | Up | 0.1946096029 |
| GSE28863_A4 | Up | 0.0891429599 |
| GSE48662 | Up | 0.0975283622 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022488 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
