HCSGD entry for SPSB1
1. General information
| Official gene symbol | SPSB1 |
|---|---|
| Entrez ID | 80176 |
| Gene full name | splA/ryanodine receptor domain and SOCS box containing 1 |
| Other gene symbols | SSB-1 SSB1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0002740359 | 0.7442563998 | 0.0453641509 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.0990010209 |
| GSE13712_SHEAR | Down | -0.5977835392 |
| GSE13712_STATIC | Down | -0.0249138555 |
| GSE19018 | Down | -0.7398069205 |
| GSE19899_A1 | Up | 1.8989953846 |
| GSE19899_A2 | Up | 3.2966002027 |
| PubMed_21979375_A1 | Up | 3.7024063249 |
| PubMed_21979375_A2 | Up | 4.2245901439 |
| GSE35957 | Down | -0.3116038533 |
| GSE36640 | Down | -0.9006242546 |
| GSE54402 | Up | 1.8634577466 |
| GSE9593 | Up | 0.7933805132 |
| GSE43922 | Up | 2.1239474417 |
| GSE24585 | Up | 0.2833070760 |
| GSE37065 | Up | 0.3185137931 |
| GSE28863_A1 | Up | 0.1851179078 |
| GSE28863_A2 | Up | 0.4633010117 |
| GSE28863_A3 | Down | -0.0990083707 |
| GSE28863_A4 | Down | -0.0827790003 |
| GSE48662 | Down | -0.0306785536 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017474 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
