HCSGD entry for IFT74
1. General information
| Official gene symbol | IFT74 |
|---|---|
| Entrez ID | 80173 |
| Gene full name | intraflagellar transport 74 homolog (Chlamydomonas) |
| Other gene symbols | CCDC2 CMG-1 CMG1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0016023 | Cytoplasmic membrane-bounded vesicle | IEA | cellular_component |
| GO:0030992 | Intraciliary transport particle B | ISS | cellular_component |
| GO:0031514 | Motile cilium | ISS | cellular_component |
| GO:0033630 | Positive regulation of cell adhesion mediated by integrin | IEA | biological_process |
| GO:0035735 | Intraciliary transport involved in cilium morphogenesis | IMP | biological_process |
| GO:0042384 | Cilium assembly | IMP | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0048487 | Beta-tubulin binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5928179932 | 0.1246214126 | 0.9999902473 | 0.6777190496 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1283016979 |
| GSE13712_SHEAR | Down | -0.3236423953 |
| GSE13712_STATIC | Up | 0.0533906287 |
| GSE19018 | Up | 0.2910415355 |
| GSE19899_A1 | Up | 0.0128370777 |
| GSE19899_A2 | Down | -0.0494849743 |
| PubMed_21979375_A1 | Up | 0.1257751292 |
| PubMed_21979375_A2 | Down | -0.2574635242 |
| GSE35957 | Down | -0.2611227482 |
| GSE36640 | Up | 0.2427231747 |
| GSE54402 | Down | -0.4116101258 |
| GSE9593 | Down | -0.0600428825 |
| GSE43922 | Down | -0.2437598880 |
| GSE24585 | Up | 0.2868625184 |
| GSE37065 | Up | 0.3480321000 |
| GSE28863_A1 | Down | -0.0798058622 |
| GSE28863_A2 | Down | -0.5843527966 |
| GSE28863_A3 | Down | -0.4512705952 |
| GSE28863_A4 | Up | 0.2092685214 |
| GSE48662 | Down | -0.1781116242 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027044 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031787 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
