HCSGD entry for ZC3H12A

1. General information

Official gene symbolZC3H12A
Entrez ID80149
Gene full namezinc finger CCCH-type containing 12A
Other gene symbolsMCPIP MCPIP1 RP3-423B22.1 dJ423B22.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIEAbiological_process
GO:0004519Endonuclease activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006915Apoptotic processIEAbiological_process
GO:0010508Positive regulation of autophagyIDAbiological_process
GO:0010628Positive regulation of gene expressionIDAbiological_process
GO:0010629Negative regulation of gene expressionIDAbiological_process
GO:0010884Positive regulation of lipid storageIDAbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0032088Negative regulation of NF-kappaB transcription factor activityIDAbiological_process
GO:0032715Negative regulation of interleukin-6 productionIDAbiological_process
GO:0032720Negative regulation of tumor necrosis factor productionIDAbiological_process
GO:0043031Negative regulation of macrophage activationICbiological_process
GO:0045019Negative regulation of nitric oxide biosynthetic processIDAbiological_process
GO:0045600Positive regulation of fat cell differentiationIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0071222Cellular response to lipopolysaccharideIDAbiological_process
GO:2000379Positive regulation of reactive oxygen species metabolic processIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.77466041180.90400506820.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.0389356116
GSE28863_A2Up0.1434143871
GSE28863_A3Up0.1054585690
GSE28863_A4Down-0.1545880136
GSE48662Up0.1350233453

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018752MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.