HCSGD entry for CALM1

1. General information

Official gene symbolCALM1
Entrez ID801
Gene full namecalmodulin 1 (phosphorylase kinase, delta)
Other gene symbolsCALML2 CAMI CPVT4 DD132 PHKD caM
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000922Spindle poleIDAcellular_component
GO:0001975Response to amphetamineIEAbiological_process
GO:0002027Regulation of heart rateIMPbiological_process
GO:0002576Platelet degranulationTASbiological_process
GO:0005509Calcium ion bindingIDA IEA ISSmolecular_function
GO:0005513Detection of calcium ionIMPbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005634NucleusIEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005737CytoplasmIEA TAScellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005876Spindle microtubuleIDAcellular_component
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0005980Glycogen catabolic processTASbiological_process
GO:0006006Glucose metabolic processTASbiological_process
GO:0006936Muscle contractionTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007190Activation of adenylate cyclase activityIEAbiological_process
GO:0007202Activation of phospholipase C activityTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0007603Phototransduction, visible lightTASbiological_process
GO:0008179Adenylate cyclase bindingIEAmolecular_function
GO:0008543Fibroblast growth factor receptor signaling pathwayTASbiological_process
GO:0010880Regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumIDAbiological_process
GO:0010881Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ionICbiological_process
GO:0016056Rhodopsin mediated signaling pathwayTASbiological_process
GO:0019722Calcium-mediated signalingIEAbiological_process
GO:0019904Protein domain specific bindingIEA IPImolecular_function
GO:0022400Regulation of rhodopsin mediated signaling pathwayTASbiological_process
GO:0030017SarcomereIDAcellular_component
GO:0030168Platelet activationTASbiological_process
GO:0030235Nitric-oxide synthase regulator activityIEAmolecular_function
GO:0030426Growth coneIEAcellular_component
GO:0030801Positive regulation of cyclic nucleotide metabolic processIDAbiological_process
GO:0031432Titin bindingIPImolecular_function
GO:0031800Type 3 metabotropic glutamate receptor bindingIEAmolecular_function
GO:0031996Thioesterase bindingIPImolecular_function
GO:0031997N-terminal myristoylation domain bindingIPImolecular_function
GO:0032465Regulation of cytokinesisIMPbiological_process
GO:0032516Positive regulation of phosphoprotein phosphatase activityIDAbiological_process
GO:0034704Calcium channel complexIDAcellular_component
GO:0035307Positive regulation of protein dephosphorylationIDAbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0043274Phospholipase bindingIPImolecular_function
GO:0043548Phosphatidylinositol 3-kinase bindingIEAmolecular_function
GO:0043647Inositol phosphate metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0044325Ion channel bindingIEA IPImolecular_function
GO:0045087Innate immune responseTASbiological_process
GO:0046209Nitric oxide metabolic processTASbiological_process
GO:0047485Protein N-terminus bindingIEAmolecular_function
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048306Calcium-dependent protein bindingIEAmolecular_function
GO:0050998Nitric-oxide synthase bindingIEAmolecular_function
GO:0050999Regulation of nitric-oxide synthase activityTASbiological_process
GO:0051000Positive regulation of nitric-oxide synthase activityIEAbiological_process
GO:0051343Positive regulation of cyclic-nucleotide phosphodiesterase activityIDAbiological_process
GO:0051412Response to corticosteroneIEAbiological_process
GO:0051592Response to calcium ionIDAbiological_process
GO:0055117Regulation of cardiac muscle contractionIMPbiological_process
GO:0060314Regulation of ryanodine-sensitive calcium-release channel activityIEAbiological_process
GO:0060315Negative regulation of ryanodine-sensitive calcium-release channel activityISSbiological_process
GO:0060316Positive regulation of ryanodine-sensitive calcium-release channel activityIDAbiological_process
GO:0072542Protein phosphatase activator activityIDAmolecular_function
GO:1901841Regulation of high voltage-gated calcium channel activityIEAbiological_process
GO:1901844Regulation of cell communication by electrical coupling involved in cardiac conductionICbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.17408684700.45775179510.81939515551.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1930075032
GSE13712_SHEARDown-0.4594725185
GSE13712_STATICDown-1.1192079175
GSE19018Down-0.4851925742
GSE19899_A1Up0.0322168593
GSE19899_A2Up0.1132848091
PubMed_21979375_A1Up0.8284470230
PubMed_21979375_A2Down-0.0728776189
GSE35957Up0.4314835710
GSE36640Up0.4155476365
GSE54402Up0.1470479187
GSE9593Up1.1678775563
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.1108447381

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT024054Proteomics;MicroarrayFunctional MTI (Weak)18668037
hsa-miR-1MIMAT0000416MIRT024054ProteomicsFunctional MTI (Weak)18668040
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.