HCSGD entry for DOCK5
1. General information
| Official gene symbol | DOCK5 |
|---|---|
| Entrez ID | 80005 |
| Gene full name | dedicator of cytokinesis 5 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IEA ISS | molecular_function |
| GO:0005737 | Cytoplasm | IDA ISS | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0043087 | Regulation of GTPase activity | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2355523460 | 0.4062504730 | 0.9193317467 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0030719962 |
| GSE13712_SHEAR | Down | -0.0651274728 |
| GSE13712_STATIC | Up | 0.2538681497 |
| GSE19018 | Up | 0.2884769178 |
| GSE19899_A1 | Up | 0.0531829844 |
| GSE19899_A2 | Down | -0.1355347009 |
| PubMed_21979375_A1 | Up | 0.2523932369 |
| PubMed_21979375_A2 | Down | -0.0525129007 |
| GSE35957 | Down | -0.0257506498 |
| GSE36640 | Down | -0.2521105087 |
| GSE54402 | Up | 0.5000024190 |
| GSE9593 | Up | 0.1272540317 |
| GSE43922 | Up | 0.0282372871 |
| GSE24585 | Down | -0.1822755090 |
| GSE37065 | Down | -0.1702340639 |
| GSE28863_A1 | Up | 0.3112640719 |
| GSE28863_A2 | Up | 0.7900079556 |
| GSE28863_A3 | Down | -0.6583073868 |
| GSE28863_A4 | Down | -0.3610724660 |
| GSE48662 | Up | 0.0544967752 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT006314 | Immunoblot//Luciferase reporter assay//qRT-PCR | Functional MTI | 22158624 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT001638 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025783 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027646 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031712 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036937 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038767 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046721 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
