HCSGD entry for CALD1
1. General information
| Official gene symbol | CALD1 |
|---|---|
| Entrez ID | 800 |
| Gene full name | caldesmon 1 |
| Other gene symbols | CDM H-CAD HCAD L-CAD LCAD NAG22 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005523 | Tropomyosin binding | TAS | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005856 | Cytoskeleton | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006928 | Cellular component movement | TAS | biological_process |
| GO:0006936 | Muscle contraction | IEA TAS | biological_process |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0017022 | Myosin binding | IEA | molecular_function |
| GO:0030016 | Myofibril | IEA | cellular_component |
| GO:0030478 | Actin cap | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9710027507 | 0.0011690247 | 0.9999902473 | 0.0647926316 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.2669845913 |
| GSE13712_SHEAR | Up | 0.0438699043 |
| GSE13712_STATIC | Down | -0.2046060353 |
| GSE19018 | Down | -0.1840068642 |
| GSE19899_A1 | Down | -0.5680075863 |
| GSE19899_A2 | Down | -0.5769159395 |
| PubMed_21979375_A1 | Down | -1.3745216411 |
| PubMed_21979375_A2 | Down | -0.3903373580 |
| GSE35957 | Up | 0.9229683190 |
| GSE36640 | Up | 0.5624603230 |
| GSE54402 | Down | -0.2322842335 |
| GSE9593 | Up | 0.1806188977 |
| GSE43922 | Down | -0.5837754273 |
| GSE24585 | Down | -0.0539847429 |
| GSE37065 | Down | -0.2839800631 |
| GSE28863_A1 | Down | -1.2087522529 |
| GSE28863_A2 | Down | -0.6657004633 |
| GSE28863_A3 | Down | -0.5264609288 |
| GSE28863_A4 | Down | -0.5619244566 |
| GSE48662 | Down | -0.1993116738 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-122-5p | MIMAT0000421 | MIRT023307 | Proteomics | Functional MTI (Weak) | 21750653 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025321 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030858 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045412 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT051318 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
