HCSGD entry for L2HGDH
1. General information
| Official gene symbol | L2HGDH |
|---|---|
| Entrez ID | 79944 |
| Gene full name | L-2-hydroxyglutarate dehydrogenase |
| Other gene symbols | C14orf160 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0006103 | 2-oxoglutarate metabolic process | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IDA | cellular_component |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0031305 | Integral component of mitochondrial inner membrane | NAS | cellular_component |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | IDA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0047545 | 2-hydroxyglutarate dehydrogenase activity | IDA | molecular_function |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6985638502 | 0.7062899206 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0784538735 |
| GSE13712_SHEAR | Up | 0.1710047804 |
| GSE13712_STATIC | Up | 0.1385079523 |
| GSE19018 | Up | 0.2317240411 |
| GSE19899_A1 | Down | -0.0871279786 |
| GSE19899_A2 | Down | -0.3681306368 |
| PubMed_21979375_A1 | Up | 0.0148633599 |
| PubMed_21979375_A2 | Down | -0.0964034672 |
| GSE35957 | Down | -0.3430867541 |
| GSE36640 | Down | -0.3710865057 |
| GSE54402 | Down | -0.0423444605 |
| GSE9593 | Down | -0.0191692817 |
| GSE43922 | Up | 0.0538824464 |
| GSE24585 | Up | 0.1024533662 |
| GSE37065 | Up | 0.3772698385 |
| GSE28863_A1 | Down | -0.0225629523 |
| GSE28863_A2 | Up | 0.0073275515 |
| GSE28863_A3 | Down | -0.0087151099 |
| GSE28863_A4 | Up | 0.0629975186 |
| GSE48662 | Down | -0.0050487629 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020698 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024689 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026454 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050528 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
