HCSGD entry for SETD6
1. General information
| Official gene symbol | SETD6 |
|---|---|
| Entrez ID | 79918 |
| Gene full name | SET domain containing 6 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0016279 | Protein-lysine N-methyltransferase activity | IDA | molecular_function |
| GO:0018026 | Peptidyl-lysine monomethylation | IDA | biological_process |
| GO:0032088 | Negative regulation of NF-kappaB transcription factor activity | IMP | biological_process |
| GO:0050727 | Regulation of inflammatory response | IMP | biological_process |
| GO:0051059 | NF-kappaB binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3926888074 | 0.1544411117 | 0.9999902473 | 0.7593955726 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2644796371 |
| GSE13712_SHEAR | Down | -0.1044501806 |
| GSE13712_STATIC | Down | -0.2164221997 |
| GSE19018 | Down | -0.6287892100 |
| GSE19899_A1 | Up | 0.0076500220 |
| GSE19899_A2 | Up | 0.2943295692 |
| PubMed_21979375_A1 | Up | 0.8028772212 |
| PubMed_21979375_A2 | Up | 0.4830322799 |
| GSE35957 | Down | -0.2583050896 |
| GSE36640 | Down | -0.8593193365 |
| GSE54402 | Up | 0.1738236176 |
| GSE9593 | Down | -0.0734688044 |
| GSE43922 | Up | 0.1378291444 |
| GSE24585 | Down | -0.4005466166 |
| GSE37065 | Down | -0.0961567141 |
| GSE28863_A1 | Down | -0.3231278360 |
| GSE28863_A2 | Down | -0.0416070875 |
| GSE28863_A3 | Up | 0.2445035112 |
| GSE28863_A4 | Up | 0.0677856704 |
| GSE48662 | Down | -0.0593451342 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT042072 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
