HCSGD entry for CYBRD1
1. General information
| Official gene symbol | CYBRD1 |
|---|---|
| Entrez ID | 79901 |
| Gene full name | cytochrome b reductase 1 |
| Other gene symbols | CYB561A2 DCYTB FRRS3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000293 | Ferric-chelate reductase activity | IDA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006879 | Cellular iron ion homeostasis | TAS | biological_process |
| GO:0010039 | Response to iron ion | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016722 | Oxidoreductase activity, oxidizing metal ions | TAS | molecular_function |
| GO:0031526 | Brush border membrane | IEA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2131211580 | 0.0056245317 | 0.8897069616 | 0.1514385087 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1431319125 |
| GSE13712_SHEAR | Down | -0.3422215446 |
| GSE13712_STATIC | Down | -0.2996223599 |
| GSE19018 | Up | 0.1344206124 |
| GSE19899_A1 | Down | -1.7632035833 |
| GSE19899_A2 | Down | -1.1188062029 |
| PubMed_21979375_A1 | Down | -2.9029666097 |
| PubMed_21979375_A2 | Down | -1.9906070545 |
| GSE35957 | Up | 1.2349409521 |
| GSE36640 | Up | 1.2972301826 |
| GSE54402 | Down | -0.9741851141 |
| GSE9593 | Up | 0.9726562120 |
| GSE43922 | Down | -1.0344312629 |
| GSE24585 | Up | 1.3581327408 |
| GSE37065 | Up | 0.1690701951 |
| GSE28863_A1 | Down | -0.2155746813 |
| GSE28863_A2 | Up | 0.0917123104 |
| GSE28863_A3 | Down | -0.1248825923 |
| GSE28863_A4 | Down | -0.2471645844 |
| GSE48662 | Up | 0.0959963937 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022211 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028908 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030691 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-301a-3p | MIMAT0000688 | MIRT044230 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049718 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
