HCSGD entry for UBA5


1. General information

Official gene symbolUBA5
Entrez ID79876
Gene full nameubiquitin-like modifier activating enzyme 5
Other gene symbolsTHIFP1 UBE1DC1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003824Catalytic activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0016235AggresomeIDAcellular_component
GO:0016616Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorIEAmolecular_function
GO:0034976Response to endoplasmic reticulum stressIDAbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048037Cofactor bindingIEAmolecular_function
GO:0071566UFM1 activating enzyme activityIDAmolecular_function
GO:0071569Protein ufmylationIDA IEA IMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.76405965580.10045024890.99999024730.6075255055

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1828229397
GSE13712_SHEARDown-0.6984530248
GSE13712_STATICDown-0.3139639461
GSE19018Down-0.3284833765
GSE19899_A1Down-0.2005616346
GSE19899_A2Down-0.3109274409
PubMed_21979375_A1Down-0.0044356386
PubMed_21979375_A2Down-0.2583803598
GSE35957Up0.1414189625
GSE36640Up0.4054929774
GSE54402Up0.1563942013
GSE9593Down-0.2157962561
GSE43922Down-0.0014965211
GSE24585Up0.0081999276
GSE37065Down-0.0069455552
GSE28863_A1Up0.2893640285
GSE28863_A2Up0.6569529624
GSE28863_A3Down-0.7747533803
GSE28863_A4Down-0.2160311190
GSE48662Down-0.1951785737

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.