HCSGD entry for CBLL1
1. General information
| Official gene symbol | CBLL1 |
|---|---|
| Entrez ID | 79872 |
| Gene full name | Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1 |
| Other gene symbols | HAKAI RNF188 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000151 | Ubiquitin ligase complex | IC | cellular_component |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0004842 | Ubiquitin-protein ligase activity | IEA ISS TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0007162 | Negative regulation of cell adhesion | IEA ISS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016337 | Cell-cell adhesion | IDA | biological_process |
| GO:0016567 | Protein ubiquitination | TAS | biological_process |
| GO:0030335 | Positive regulation of cell migration | IEA ISS | biological_process |
| GO:0042802 | Identical protein binding | IEA | molecular_function |
| GO:0045807 | Positive regulation of endocytosis | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1173540481 | 0.8731579841 | 0.7023364939 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2516950210 |
| GSE13712_SHEAR | Up | 0.5793328057 |
| GSE13712_STATIC | Up | 0.1537711469 |
| GSE19018 | Down | -0.7110695717 |
| GSE19899_A1 | Up | 0.1623459362 |
| GSE19899_A2 | Up | 0.4066740941 |
| PubMed_21979375_A1 | Up | 0.4758430086 |
| PubMed_21979375_A2 | Up | 0.1524201591 |
| GSE35957 | Down | -0.1396266193 |
| GSE36640 | Down | -0.0306463948 |
| GSE54402 | Up | 0.2042983029 |
| GSE9593 | Up | 0.0960688746 |
| GSE43922 | Down | -0.0007576406 |
| GSE24585 | Up | 0.0034471374 |
| GSE37065 | Up | 0.1457952640 |
| GSE28863_A1 | Up | 0.1973986477 |
| GSE28863_A2 | Up | 0.5929295070 |
| GSE28863_A3 | Up | 0.0525141118 |
| GSE28863_A4 | Down | -0.2659454229 |
| GSE48662 | Down | -0.0386204239 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-203a | MIMAT0000264 | MIRT007353 | qRT-PCR//Western blot | Functional MTI | 23285092 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029151 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
