HCSGD entry for CPSF7
1. General information
| Official gene symbol | CPSF7 |
|---|---|
| Entrez ID | 79869 |
| Gene full name | cleavage and polyadenylation specific factor 7, 59kDa |
| Other gene symbols | CFIm59 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000398 | MRNA splicing, via spliceosome | TAS | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005849 | MRNA cleavage factor complex | IDA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006369 | Termination of RNA polymerase II transcription | TAS | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0031124 | MRNA 3'-end processing | TAS | biological_process |
| GO:0051262 | Protein tetramerization | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4944796664 | 0.7294345694 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0980201131 |
| GSE13712_SHEAR | Up | 0.1122562796 |
| GSE13712_STATIC | Down | -0.1307302345 |
| GSE19018 | Down | -0.1620068914 |
| GSE19899_A1 | Down | -0.0658468561 |
| GSE19899_A2 | Down | -0.0608321865 |
| PubMed_21979375_A1 | Down | -0.1249141161 |
| PubMed_21979375_A2 | Up | 0.6723143220 |
| GSE35957 | Up | 0.0145648344 |
| GSE36640 | Down | -0.3687841259 |
| GSE54402 | Up | 0.0467241685 |
| GSE9593 | Down | -0.1013075277 |
| GSE43922 | Up | 0.0505815945 |
| GSE24585 | Up | 0.0288556109 |
| GSE37065 | Up | 0.0490419660 |
| GSE28863_A1 | Up | 0.2090790053 |
| GSE28863_A2 | Up | 0.3265161842 |
| GSE28863_A3 | Down | -0.1962710286 |
| GSE28863_A4 | Down | -0.0265832046 |
| GSE48662 | Up | 0.1356530996 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027174 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031997 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30c-2-3p | MIMAT0004550 | MIRT038696 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041769 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043890 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046265 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
