HCSGD entry for PDZD3

1. General information

Official gene symbolPDZD3
Entrez ID79849
Gene full namePDZ domain containing 3
Other gene symbolsIKEPP NHERF4 PDZK2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:0005903Brush borderIDAcellular_component
GO:0006811Ion transportNASbiological_process
GO:0006833Water transportNASbiological_process
GO:0007168Receptor guanylyl cyclase signaling pathwayICbiological_process
GO:0008022Protein C-terminus bindingIPImolecular_function
GO:0008200Ion channel inhibitor activityTASmolecular_function
GO:0009636Response to toxic substanceTASbiological_process
GO:0019934CGMP-mediated signalingNASbiological_process
GO:0030251Guanylate cyclase inhibitor activityIDAmolecular_function
GO:0030827Negative regulation of cGMP biosynthetic processTASbiological_process
GO:0031279Regulation of cyclase activityIDAbiological_process
GO:0031282Regulation of guanylate cyclase activityIDAbiological_process
GO:0031283Negative regulation of guanylate cyclase activityIDAbiological_process
GO:0035003Subapical complexIDAcellular_component
GO:0043086Negative regulation of catalytic activityIDAbiological_process
GO:0045177Apical part of cellIDAcellular_component
GO:0050790Regulation of catalytic activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91495951900.52873247220.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1240054555
GSE13712_SHEARUp0.0172557768
GSE13712_STATICDown-0.0934381502
GSE19018Down-0.0558934129
GSE19899_A1Down-0.0096022037
GSE19899_A2Up0.1033683450
PubMed_21979375_A1Down-0.0786072323
PubMed_21979375_A2Down-0.2795959510
GSE35957Up0.1528351168
GSE36640Down-0.0309254618
GSE54402Up0.0475454160
GSE9593Up0.0224649689
GSE43922Up0.0428069258
GSE24585Down-0.1185143790
GSE37065Down-0.0204574369
GSE28863_A1Down-0.1674475119
GSE28863_A2Down-0.0985069021
GSE28863_A3Up0.1983415656
GSE28863_A4Up0.0660372278
GSE48662Down-0.0202705406

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.