HCSGD entry for ISOC2
1. General information
| Official gene symbol | ISOC2 |
|---|---|
| Entrez ID | 79763 |
| Gene full name | isochorismatase domain containing 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0031648 | Protein destabilization | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8001063371 | 0.0636606208 | 0.9999902473 | 0.4758768445 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3512751821 |
| GSE13712_SHEAR | Down | -0.2778419590 |
| GSE13712_STATIC | Up | 0.1737902290 |
| GSE19018 | Down | -0.0724044644 |
| GSE19899_A1 | Down | -0.5636065107 |
| GSE19899_A2 | Down | -0.6372671358 |
| PubMed_21979375_A1 | Up | 1.0542977545 |
| PubMed_21979375_A2 | Down | -0.7620742929 |
| GSE35957 | Down | -0.5821637452 |
| GSE36640 | Down | -0.0410342039 |
| GSE54402 | Up | 0.0839541654 |
| GSE9593 | Down | -0.3385674890 |
| GSE43922 | Down | -0.2078357250 |
| GSE24585 | Down | -0.3765965585 |
| GSE37065 | Down | -0.1165433205 |
| GSE28863_A1 | Down | -0.2648422477 |
| GSE28863_A2 | Down | -0.0216322133 |
| GSE28863_A3 | Up | 0.0049911602 |
| GSE28863_A4 | Up | 0.0798910202 |
| GSE48662 | Up | 0.2710262027 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030140 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-769-3p | MIMAT0003887 | MIRT039080 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041590 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-342-3p | MIMAT0000753 | MIRT043676 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052263 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
