HCSGD entry for SLC25A22


1. General information

Official gene symbolSLC25A22
Entrez ID79751
Gene full namesolute carrier family 25 (mitochondrial carrier: glutamate), member 22
Other gene symbolsEIEE3 GC1 NET44
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003333Amino acid transmembrane transportIDAbiological_process
GO:0005313L-glutamate transmembrane transporter activityIDAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005739MitochondrionIDA IEAcellular_component
GO:0005743Mitochondrial inner membraneIDAcellular_component
GO:0006810TransportIEAbiological_process
GO:0015293Symporter activityIEAmolecular_function
GO:0015813L-glutamate transportIDAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0034220Ion transmembrane transportIDAbiological_process
GO:0055085Transmembrane transportIEAbiological_process
GO:1902475L-alpha-amino acid transmembrane transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04899895520.93036478860.48742191991.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0566673684
GSE13712_SHEARUp0.2936780673
GSE13712_STATICUp0.1331698615
GSE19018Up0.0752144520
GSE19899_A1Down-0.0357565448
GSE19899_A2Up1.0478979300
PubMed_21979375_A1Up0.4040930799
PubMed_21979375_A2Up1.4135293097
GSE35957Down-0.2761015890
GSE36640Up0.1109847603
GSE54402Up0.7670415050
GSE9593Down-0.0810290594
GSE43922Up0.0424196216
GSE24585Up0.0007744120
GSE37065Down-0.0693406027
GSE28863_A1Up0.0752748165
GSE28863_A2Up0.2092758834
GSE28863_A3Up0.0301467828
GSE28863_A4Up0.0601312018
GSE48662Up0.1373731202

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT001332pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-16-5pMIMAT0000069MIRT001415pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.