HCSGD entry for TEFM
1. General information
| Official gene symbol | TEFM |
|---|---|
| Entrez ID | 79736 |
| Gene full name | transcription elongation factor, mitochondrial |
| Other gene symbols | C17orf42 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005759 | Mitochondrial matrix | IDA | cellular_component |
| GO:0006119 | Oxidative phosphorylation | IMP | biological_process |
| GO:0006259 | DNA metabolic process | IDA | biological_process |
| GO:0006264 | Mitochondrial DNA replication | IMP | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006390 | Transcription from mitochondrial promoter | IMP | biological_process |
| GO:0008821 | Crossover junction endodeoxyribonuclease activity | IDA | molecular_function |
| GO:0030337 | DNA polymerase processivity factor activity | IDA | molecular_function |
| GO:0030529 | Ribonucleoprotein complex | IDA | cellular_component |
| GO:0042645 | Mitochondrial nucleoid | IDA | cellular_component |
| GO:0050790 | Regulation of catalytic activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4592949318 | 0.4780761027 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1732028055 |
| GSE13712_SHEAR | Up | 0.2084909017 |
| GSE13712_STATIC | Up | 0.1050766064 |
| GSE19018 | Down | -0.4626622910 |
| GSE19899_A1 | Up | 0.2674262483 |
| GSE19899_A2 | Down | -0.1327489726 |
| PubMed_21979375_A1 | Up | 0.1420944581 |
| PubMed_21979375_A2 | Up | 0.0650694642 |
| GSE35957 | Down | -0.1945117099 |
| GSE36640 | Down | -0.0016853608 |
| GSE54402 | Up | 0.1763770851 |
| GSE9593 | Down | -0.2115813739 |
| GSE43922 | Up | 0.0592457892 |
| GSE24585 | Up | 0.0630947607 |
| GSE37065 | Down | -0.0857619110 |
| GSE28863_A1 | Up | 0.1563648665 |
| GSE28863_A2 | Down | -0.0365064436 |
| GSE28863_A3 | Down | -0.2376032731 |
| GSE28863_A4 | Up | 0.1968887450 |
| GSE48662 | Down | -0.2973413466 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-17-5p | MIMAT0000070 | MIRT050920 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
