HCSGD entry for E2F8


1. General information

Official gene symbolE2F8
Entrez ID79733
Gene full nameE2F transcription factor 8
Other gene symbolsE2F-8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEA ISSbiological_process
GO:0001047Core promoter bindingIDAmolecular_function
GO:0001890Placenta developmentISSbiological_process
GO:0002040Sprouting angiogenesisIEA IMPbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEA IMPmolecular_function
GO:0003714Transcription corepressor activityIEA ISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005667Transcription factor complexIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0008283Cell proliferationIEAbiological_process
GO:0032466Negative regulation of cytokinesisIEA ISSbiological_process
GO:0032877Positive regulation of DNA endoreduplicationIEA ISSbiological_process
GO:0033301Cell cycle comprising mitosis without cytokinesisIEA ISSbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIMPbiological_process
GO:0060707Trophoblast giant cell differentiationIEA ISSbiological_process
GO:0060718Chorionic trophoblast cell differentiationIEA ISSbiological_process
GO:0070365Hepatocyte differentiationIEA ISSbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99678323390.00018680900.99999024730.0245860000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3841884732
GSE13712_SHEARDown-0.8915597356
GSE13712_STATICDown-0.2354632335
GSE19018Down-0.0526770378
GSE19899_A1Down-0.4518983264
GSE19899_A2Down-4.5267172397
PubMed_21979375_A1Down-0.6415855524
PubMed_21979375_A2Down-3.8294610956
GSE35957Down-1.8542206552
GSE36640Down-4.1736229502
GSE54402Down-0.3805715761
GSE9593Down-0.8894236854
GSE43922Down-0.2751406955
GSE24585Up0.1502979519
GSE37065Down-0.1993976647
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.8003486766

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-215-5pMIMAT0000272MIRT024943MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026752MicroarrayFunctional MTI (Weak)19074876
hsa-miR-19b-3pMIMAT0000074MIRT031294SequencingFunctional MTI (Weak)20371350
hsa-miR-125a-3pMIMAT0004602MIRT038639CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.