HCSGD entry for E2F8
1. General information
Official gene symbol | E2F8 |
---|---|
Entrez ID | 79733 |
Gene full name | E2F transcription factor 8 |
Other gene symbols | E2F-8 |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA ISS | biological_process |
GO:0001047 | Core promoter binding | IDA | molecular_function |
GO:0001890 | Placenta development | ISS | biological_process |
GO:0002040 | Sprouting angiogenesis | IEA IMP | biological_process |
GO:0003677 | DNA binding | IEA | molecular_function |
GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA IMP | molecular_function |
GO:0003714 | Transcription corepressor activity | IEA ISS | molecular_function |
GO:0005515 | Protein binding | IPI | molecular_function |
GO:0005634 | Nucleus | IEA | cellular_component |
GO:0005667 | Transcription factor complex | IEA | cellular_component |
GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
GO:0008283 | Cell proliferation | IEA | biological_process |
GO:0032466 | Negative regulation of cytokinesis | IEA ISS | biological_process |
GO:0032877 | Positive regulation of DNA endoreduplication | IEA ISS | biological_process |
GO:0033301 | Cell cycle comprising mitosis without cytokinesis | IEA ISS | biological_process |
GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IMP | biological_process |
GO:0060707 | Trophoblast giant cell differentiation | IEA ISS | biological_process |
GO:0060718 | Chorionic trophoblast cell differentiation | IEA ISS | biological_process |
GO:0070365 | Hepatocyte differentiation | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.9967832339 | 0.0001868090 | 0.9999902473 | 0.0245860000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Down | -0.3841884732 |
GSE13712_SHEAR | Down | -0.8915597356 |
GSE13712_STATIC | Down | -0.2354632335 |
GSE19018 | Down | -0.0526770378 |
GSE19899_A1 | Down | -0.4518983264 |
GSE19899_A2 | Down | -4.5267172397 |
PubMed_21979375_A1 | Down | -0.6415855524 |
PubMed_21979375_A2 | Down | -3.8294610956 |
GSE35957 | Down | -1.8542206552 |
GSE36640 | Down | -4.1736229502 |
GSE54402 | Down | -0.3805715761 |
GSE9593 | Down | -0.8894236854 |
GSE43922 | Down | -0.2751406955 |
GSE24585 | Up | 0.1502979519 |
GSE37065 | Down | -0.1993976647 |
GSE28863_A1 | - | - |
GSE28863_A2 | - | - |
GSE28863_A3 | - | - |
GSE28863_A4 | - | - |
GSE48662 | Down | -0.8003486766 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-215-5p | MIMAT0000272 | MIRT024943 | Microarray | Functional MTI (Weak) | 19074876 |
hsa-miR-192-5p | MIMAT0000222 | MIRT026752 | Microarray | Functional MTI (Weak) | 19074876 |
hsa-miR-19b-3p | MIMAT0000074 | MIRT031294 | Sequencing | Functional MTI (Weak) | 20371350 |
hsa-miR-125a-3p | MIMAT0004602 | MIRT038639 | CLASH | Functional MTI (Weak) | 23622248 |
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