HCSGD entry for NARS2
1. General information
| Official gene symbol | NARS2 |
|---|---|
| Entrez ID | 79731 |
| Gene full name | asparaginyl-tRNA synthetase 2, mitochondrial (putative) |
| Other gene symbols | SLM5 asnRS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0004816 | Asparagine-tRNA ligase activity | IEA ISS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005739 | Mitochondrion | ISS | cellular_component |
| GO:0005759 | Mitochondrial matrix | IEA | cellular_component |
| GO:0006418 | TRNA aminoacylation for protein translation | TAS | biological_process |
| GO:0006421 | Asparaginyl-tRNA aminoacylation | IEA ISS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9023537100 | 0.0309967440 | 0.9999902473 | 0.3311875101 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1477225558 |
| GSE13712_SHEAR | Down | -0.0752312088 |
| GSE13712_STATIC | Down | -0.0200828458 |
| GSE19018 | Down | -0.2175001866 |
| GSE19899_A1 | Up | 0.0566999537 |
| GSE19899_A2 | Down | -0.0969106376 |
| PubMed_21979375_A1 | Up | 0.6288674918 |
| PubMed_21979375_A2 | Down | -0.2182991799 |
| GSE35957 | Down | -0.7862856278 |
| GSE36640 | Down | -1.3964676965 |
| GSE54402 | Up | 0.0908047713 |
| GSE9593 | Down | -0.4272868102 |
| GSE43922 | Down | -0.0003983842 |
| GSE24585 | Down | -0.6788424843 |
| GSE37065 | Down | -0.1114352211 |
| GSE28863_A1 | Up | 0.0854911530 |
| GSE28863_A2 | Up | 0.0628176175 |
| GSE28863_A3 | Down | -0.6385243624 |
| GSE28863_A4 | Up | 0.0678420526 |
| GSE48662 | Down | -0.5430520651 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029094 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031482 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032305 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
