HCSGD entry for NLRX1
1. General information
| Official gene symbol | NLRX1 |
|---|---|
| Entrez ID | 79671 |
| Gene full name | NLR family member X1 |
| Other gene symbols | CLR11.3 DLNB26 NOD26 NOD5 NOD9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | TAS | cellular_component |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0032480 | Negative regulation of type I interferon production | TAS | biological_process |
| GO:0032688 | Negative regulation of interferon-beta production | IEA | biological_process |
| GO:0032715 | Negative regulation of interleukin-6 production | IEA | biological_process |
| GO:0039536 | Negative regulation of RIG-I signaling pathway | IEA | biological_process |
| GO:0043124 | Negative regulation of I-kappaB kinase/NF-kappaB signaling | IEA | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0045824 | Negative regulation of innate immune response | IEA | biological_process |
| GO:0050728 | Negative regulation of inflammatory response | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4276455036 | 0.4567439687 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2428143970 |
| GSE13712_SHEAR | Up | 0.4313069042 |
| GSE13712_STATIC | Up | 0.3784476369 |
| GSE19018 | Down | -0.0658635048 |
| GSE19899_A1 | Down | -0.2506491423 |
| GSE19899_A2 | Up | 0.1506597380 |
| PubMed_21979375_A1 | Up | 0.1092743236 |
| PubMed_21979375_A2 | Up | 0.4213564357 |
| GSE35957 | Up | 0.2577995837 |
| GSE36640 | Up | 0.3709831333 |
| GSE54402 | Down | -0.3947604995 |
| GSE9593 | Up | 0.1689394539 |
| GSE43922 | Up | 0.0487650581 |
| GSE24585 | Up | 0.0818061531 |
| GSE37065 | Down | -0.2536117286 |
| GSE28863_A1 | Down | -0.0156724164 |
| GSE28863_A2 | Down | -0.0565405147 |
| GSE28863_A3 | Down | -0.0155039582 |
| GSE28863_A4 | Down | -0.0615861803 |
| GSE48662 | Down | -0.0281347825 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022772 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043504 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
