HCSGD entry for NEIL1

1. General information

Official gene symbolNEIL1
Entrez ID79661
Gene full namenei endonuclease VIII-like 1 (E. coli)
Other gene symbolsFPG1 NEI1 hFPG1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003684Damaged DNA bindingIEAmolecular_function
GO:0003906DNA-(apurinic or apyrimidinic site) lyase activityIEAmolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005694ChromosomeIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005815Microtubule organizing centerIEAcellular_component
GO:0006281DNA repairIEAbiological_process
GO:0006284Base-excision repairIDA IEAbiological_process
GO:0006289Nucleotide-excision repairIEAbiological_process
GO:0006979Response to oxidative stressIDAbiological_process
GO:0008022Protein C-terminus bindingIPImolecular_function
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0016798Hydrolase activity, acting on glycosyl bondsIDAmolecular_function
GO:0016799Hydrolase activity, hydrolyzing N-glycosyl compoundsIEAmolecular_function
GO:0016829Lyase activityIEAmolecular_function
GO:0019104DNA N-glycosylase activityIEAmolecular_function
GO:0032074Negative regulation of nuclease activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00320539490.99982445200.15234133571.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.4618489512

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

TrisDB03754 EXPT03072

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017116MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.