HCSGD entry for DYNC2H1
1. General information
| Official gene symbol | DYNC2H1 |
|---|---|
| Entrez ID | 79659 |
| Gene full name | dynein, cytoplasmic 2, heavy chain 1 |
| Other gene symbols | ATD3 DHC1b DHC2 DNCH2 DYH1B SRPS2B hdhc11 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001539 | Ciliary or bacterial-type flagellar motility | IEA | biological_process |
| GO:0003774 | Motor activity | NAS | molecular_function |
| GO:0003777 | Microtubule motor activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005874 | Microtubule | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007018 | Microtubule-based movement | IEA | biological_process |
| GO:0007030 | Golgi organization | IDA | biological_process |
| GO:0007368 | Determination of left/right symmetry | IEA | biological_process |
| GO:0008105 | Asymmetric protein localization | IEA | biological_process |
| GO:0009953 | Dorsal/ventral pattern formation | IEA | biological_process |
| GO:0016485 | Protein processing | IEA | biological_process |
| GO:0016887 | ATPase activity | IEA | molecular_function |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0021522 | Spinal cord motor neuron differentiation | IEA | biological_process |
| GO:0030031 | Cell projection assembly | IEA | biological_process |
| GO:0030286 | Dynein complex | IEA | cellular_component |
| GO:0030326 | Embryonic limb morphogenesis | IEA | biological_process |
| GO:0030900 | Forebrain development | IEA | biological_process |
| GO:0031512 | Motile primary cilium | IEA | cellular_component |
| GO:0042384 | Cilium assembly | IEA | biological_process |
| GO:0045177 | Apical part of cell | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2234111128 | 0.1431395274 | 0.9040289793 | 0.7288879157 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1088512663 |
| GSE13712_SHEAR | Down | -0.5492877139 |
| GSE13712_STATIC | Down | -0.2080003499 |
| GSE19018 | Down | -0.0585553562 |
| GSE19899_A1 | Up | 0.0210481215 |
| GSE19899_A2 | Down | -0.2637121186 |
| PubMed_21979375_A1 | Down | -0.2678009133 |
| PubMed_21979375_A2 | Down | -0.0167381389 |
| GSE35957 | Up | 0.2435968272 |
| GSE36640 | Down | -0.1736494267 |
| GSE54402 | Up | 0.3862808220 |
| GSE9593 | Up | 0.3020072378 |
| GSE43922 | Down | -0.5018768860 |
| GSE24585 | Down | -0.0524039171 |
| GSE37065 | Down | -0.3854429828 |
| GSE28863_A1 | Up | 1.4416178047 |
| GSE28863_A2 | Up | 0.7701674503 |
| GSE28863_A3 | Down | -0.5042037874 |
| GSE28863_A4 | Up | 0.1593119719 |
| GSE48662 | Down | -0.2323274233 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020503 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022185 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043435 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045954 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052554 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
