HCSGD entry for ARHGAP10
1. General information
| Official gene symbol | ARHGAP10 |
|---|---|
| Entrez ID | 79658 |
| Gene full name | Rho GTPase activating protein 10 |
| Other gene symbols | GRAF2 PS-GAP PSGAP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005100 | Rho GTPase activator activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0007010 | Cytoskeleton organization | IEA | biological_process |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | TAS | biological_process |
| GO:0042981 | Regulation of apoptotic process | TAS | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IEA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7947482656 | 0.2063875499 | 0.9999902473 | 0.8810078482 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1147997799 |
| GSE13712_SHEAR | Up | 0.1196206737 |
| GSE13712_STATIC | Up | 0.0392032697 |
| GSE19018 | Up | 0.1929695127 |
| GSE19899_A1 | Down | -0.4163330967 |
| GSE19899_A2 | Down | -0.5031257384 |
| PubMed_21979375_A1 | Up | 0.0158831372 |
| PubMed_21979375_A2 | Down | -0.0988222904 |
| GSE35957 | Up | 0.3048748746 |
| GSE36640 | Down | -0.0224202942 |
| GSE54402 | Down | -0.2021918143 |
| GSE9593 | Up | 0.1240984302 |
| GSE43922 | Down | -0.0575959437 |
| GSE24585 | Down | -0.0643675169 |
| GSE37065 | Up | 0.1499379938 |
| GSE28863_A1 | Up | 0.3925012347 |
| GSE28863_A2 | Down | -0.1405529938 |
| GSE28863_A3 | Down | -0.5187541018 |
| GSE28863_A4 | Down | -0.1158175704 |
| GSE48662 | Down | -0.0339690057 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-17-5p | MIMAT0000070 | MIRT051013 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
