HCSGD entry for RNASEH2B


1. General information

Official gene symbolRNASEH2B
Entrez ID79621
Gene full nameribonuclease H2, subunit B
Other gene symbolsAGS2 DLEU8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001701In utero embryonic developmentIEAbiological_process
GO:0004523RNA-DNA hybrid ribonuclease activityIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006401RNA catabolic processIDAbiological_process
GO:0009259Ribonucleotide metabolic processIEAbiological_process
GO:0010389Regulation of G2/M transition of mitotic cell cycleIEAbiological_process
GO:0010629Negative regulation of gene expressionIEAbiological_process
GO:0032299Ribonuclease H2 complexIDAcellular_component
GO:0048146Positive regulation of fibroblast proliferationIEAbiological_process
GO:2000001Regulation of DNA damage checkpointIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99003991490.01369451770.99999024730.2304522045

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0026345776
GSE13712_SHEARDown-0.0335749345
GSE13712_STATICUp0.0355197461
GSE19018Down-0.1969153511
GSE19899_A1Down-0.1062307402
GSE19899_A2Down-0.7616255420
PubMed_21979375_A1Up0.2126030134
PubMed_21979375_A2Down-0.6597534230
GSE35957Down-0.2411808593
GSE36640Down-0.5010308637
GSE54402Down-0.4428846498
GSE9593Down-0.3154058099
GSE43922Down-0.6387865130
GSE24585Down-0.4814435244
GSE37065Down-0.1969384029
GSE28863_A1Up0.1849937762
GSE28863_A2Down-0.2921429280
GSE28863_A3Down-0.4221120153
GSE28863_A4Up0.0735341969
GSE48662Down-0.5896070565

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-328-3pMIMAT0000752MIRT043749CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.