HCSGD entry for RNF128
1. General information
| Official gene symbol | RNF128 |
|---|---|
| Entrez ID | 79589 |
| Gene full name | ring finger protein 128, E3 ubiquitin protein ligase |
| Other gene symbols | GRAIL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IEA | molecular_function |
| GO:0005770 | Late endosome | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0012505 | Endomembrane system | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0042036 | Negative regulation of cytokine biosynthetic process | IEA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0006526082 | 0.3106697428 | 0.0740632911 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 2.9505550831 |
| GSE13712_SHEAR | Down | -0.1408675443 |
| GSE13712_STATIC | Down | -0.2382609290 |
| GSE19018 | Down | -1.9509600153 |
| GSE19899_A1 | Up | 4.9806866819 |
| GSE19899_A2 | Up | 2.4548310108 |
| PubMed_21979375_A1 | Up | 1.2899107432 |
| PubMed_21979375_A2 | Up | 0.9807215224 |
| GSE35957 | Up | 0.8147385513 |
| GSE36640 | Up | 0.7873981273 |
| GSE54402 | Up | 3.4228956722 |
| GSE9593 | Up | 0.1033537531 |
| GSE43922 | Up | 1.0279527616 |
| GSE24585 | Down | -0.8657197102 |
| GSE37065 | Up | 0.1280503436 |
| GSE28863_A1 | Down | -0.1249052425 |
| GSE28863_A2 | Down | -0.0552321548 |
| GSE28863_A3 | Down | -0.0034410783 |
| GSE28863_A4 | Up | 0.0546942220 |
| GSE48662 | Up | 0.0019930262 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-132-3p | MIMAT0000426 | MIRT021799 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025823 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT048992 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
