HCSGD entry for ATP13A3
1. General information
| Official gene symbol | ATP13A3 |
|---|---|
| Entrez ID | 79572 |
| Gene full name | ATPase type 13A3 |
| Other gene symbols | AFURS1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0006812 | Cation transport | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016887 | ATPase activity | IEA | molecular_function |
| GO:0019829 | Cation-transporting ATPase activity | IEA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0298875461 | 0.3003422134 | 0.4003410178 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0685620602 |
| GSE13712_SHEAR | Up | 0.7721747990 |
| GSE13712_STATIC | Up | 0.6351375498 |
| GSE19018 | Down | -1.0149086006 |
| GSE19899_A1 | Down | -0.3400088599 |
| GSE19899_A2 | Up | 0.7098579722 |
| PubMed_21979375_A1 | Up | 0.2261820548 |
| PubMed_21979375_A2 | Up | 0.8130737360 |
| GSE35957 | Up | 0.9737498214 |
| GSE36640 | Up | 0.2278732209 |
| GSE54402 | Up | 0.5007196727 |
| GSE9593 | Up | 0.5088722671 |
| GSE43922 | Up | 0.0152884856 |
| GSE24585 | Down | -0.0110539928 |
| GSE37065 | Up | 0.3422076649 |
| GSE28863_A1 | Down | -0.4860133774 |
| GSE28863_A2 | Up | 0.6933083534 |
| GSE28863_A3 | Down | -0.6603122911 |
| GSE28863_A4 | Down | -0.2814226352 |
| GSE48662 | Down | -0.0586054445 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-590-3p | MIMAT0004801 | MIRT016221 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-122-5p | MIMAT0000421 | MIRT023239 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027039 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027500 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031517 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-150-5p | MIMAT0000451 | MIRT045387 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-182-5p | MIMAT0000259 | MIRT047218 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 11867234 | Cloning the AFURS1 gene which is up-regulated in senescent human parenchymal kidney cells |
| 11867234 | According to the GenBank database AFURS1 is mapped to the sequence segment NT_005535 |
| 11867234 | The AFURS1 gene might have a role in cellular aging and tumor suppression as well |
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