HCSGD entry for THOC6
1. General information
| Official gene symbol | THOC6 |
|---|---|
| Entrez ID | 79228 |
| Gene full name | THO complex 6 homolog (Drosophila) |
| Other gene symbols | WDR58 fSAP35 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000346 | Transcription export complex | IDA | cellular_component |
| GO:0000347 | THO complex | IDA | cellular_component |
| GO:0000445 | THO complex part of transcription export complex | IDA | cellular_component |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0006406 | MRNA export from nucleus | IDA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007417 | Central nervous system development | IMP | biological_process |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
| GO:0043066 | Negative regulation of apoptotic process | IMP | biological_process |
| GO:0046784 | Viral mRNA export from host cell nucleus | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7193535010 | 0.0498807454 | 0.9999902473 | 0.4177254534 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.9015707718 |
| GSE13712_SHEAR | Up | 0.2302958407 |
| GSE13712_STATIC | Down | -0.5598011521 |
| GSE19018 | Up | 0.2612889790 |
| GSE19899_A1 | Down | -0.1987250579 |
| GSE19899_A2 | Down | -0.7774271137 |
| PubMed_21979375_A1 | Up | 0.3348574136 |
| PubMed_21979375_A2 | Down | -0.4084685486 |
| GSE35957 | Down | -0.5126341985 |
| GSE36640 | Down | -0.3256418663 |
| GSE54402 | Down | -0.0050716892 |
| GSE9593 | Down | -0.6996855623 |
| GSE43922 | Down | -0.2555071391 |
| GSE24585 | Down | -0.5527936093 |
| GSE37065 | Up | 0.0094758360 |
| GSE28863_A1 | Up | 0.2702227510 |
| GSE28863_A2 | Up | 0.1967981923 |
| GSE28863_A3 | Up | 0.1620806572 |
| GSE28863_A4 | Up | 0.0825202499 |
| GSE48662 | Up | 0.3820961910 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022722 | Proteomics;Microarray | Non-Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
