HCSGD entry for IRX3
1. General information
| Official gene symbol | IRX3 |
|---|---|
| Entrez ID | 79191 |
| Gene full name | iroquois homeobox 3 |
| Other gene symbols | IRX-1 IRXB1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001656 | Metanephros development | IEA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007498 | Mesoderm development | IEA | biological_process |
| GO:0030424 | Axon | IEA | cellular_component |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045665 | Negative regulation of neuron differentiation | IEA | biological_process |
| GO:0045666 | Positive regulation of neuron differentiation | IEA | biological_process |
| GO:0072086 | Specification of loop of Henle identity | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2164934995 | 0.3709497815 | 0.8956794795 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4391286735 |
| GSE13712_SHEAR | Up | 0.0741418267 |
| GSE13712_STATIC | Up | 0.0558993500 |
| GSE19018 | Down | -0.0586739571 |
| GSE19899_A1 | Down | -0.0622222693 |
| GSE19899_A2 | Up | 0.2820710383 |
| PubMed_21979375_A1 | Down | -0.2640421087 |
| PubMed_21979375_A2 | Up | 0.3936191655 |
| GSE35957 | Down | -0.7664725588 |
| GSE36640 | Down | -0.1094615566 |
| GSE54402 | Up | 0.2809359457 |
| GSE9593 | Down | -0.5626783628 |
| GSE43922 | Up | 0.1439378037 |
| GSE24585 | Up | 0.5553217622 |
| GSE37065 | Down | -0.4485352178 |
| GSE28863_A1 | Down | -0.0935084154 |
| GSE28863_A2 | Down | -0.2459372814 |
| GSE28863_A3 | Up | 0.1569749112 |
| GSE28863_A4 | Up | 0.0330153707 |
| GSE48662 | Up | 0.3433468404 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
