HCSGD entry for TMEM43
1. General information
| Official gene symbol | TMEM43 |
|---|---|
| Entrez ID | 79188 |
| Gene full name | transmembrane protein 43 |
| Other gene symbols | ARVC5 ARVD5 EDMD7 LUMA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005637 | Nuclear inner membrane | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8656584856 | 0.0342375404 | 0.9999902473 | 0.3496958867 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2919773392 |
| GSE13712_SHEAR | Up | 0.1058911741 |
| GSE13712_STATIC | Down | -0.0272824425 |
| GSE19018 | Down | -0.0469476654 |
| GSE19899_A1 | Down | -0.6239079834 |
| GSE19899_A2 | Down | -0.2233458831 |
| PubMed_21979375_A1 | Down | -0.5957414465 |
| PubMed_21979375_A2 | Down | -0.1597450009 |
| GSE35957 | Down | -0.1404966191 |
| GSE36640 | Down | -0.1116449480 |
| GSE54402 | Down | -0.2818412217 |
| GSE9593 | Up | 0.0251617358 |
| GSE43922 | Down | -0.5069456408 |
| GSE24585 | Down | -0.4506350857 |
| GSE37065 | Down | -0.0647201461 |
| GSE28863_A1 | Up | 1.1185882293 |
| GSE28863_A2 | Up | 0.6450460716 |
| GSE28863_A3 | Down | -0.1902559750 |
| GSE28863_A4 | Down | -0.2711407652 |
| GSE48662 | Down | -0.2348084287 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001406 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT001406 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022952 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025854 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027185 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046472 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 24804545 | The present study attempts to explore the effect of PRIMA-1 on DNA methylation in a panel of thyroid cancer cell lines using luminometric methylation assay (LUMA) |
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