HCSGD entry for FBXL15
1. General information
| Official gene symbol | FBXL15 |
|---|---|
| Entrez ID | 79176 |
| Gene full name | F-box and leucine-rich repeat protein 15 |
| Other gene symbols | FBXO37 Fbl15 JET PSD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | IMP | biological_process |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0009953 | Dorsal/ventral pattern formation | ISS | biological_process |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0019005 | SCF ubiquitin ligase complex | IDA | cellular_component |
| GO:0030282 | Bone mineralization | ISS | biological_process |
| GO:0030513 | Positive regulation of BMP signaling pathway | IMP | biological_process |
| GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1721202576 | 0.7844942707 | 0.8146695379 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3602179393 |
| GSE13712_SHEAR | Down | -0.6131563630 |
| GSE13712_STATIC | Down | -0.1034320294 |
| GSE19018 | Up | 0.0376771579 |
| GSE19899_A1 | Down | -0.0642133535 |
| GSE19899_A2 | Up | 1.3295299027 |
| PubMed_21979375_A1 | Up | 0.7590021136 |
| PubMed_21979375_A2 | Up | 0.9948908077 |
| GSE35957 | Up | 0.0324034768 |
| GSE36640 | Up | 0.1926402142 |
| GSE54402 | Up | 0.0942134466 |
| GSE9593 | Down | -0.0949889942 |
| GSE43922 | Up | 0.0434857407 |
| GSE24585 | Down | -0.0125131457 |
| GSE37065 | Down | -0.0261502678 |
| GSE28863_A1 | Down | -0.1574497301 |
| GSE28863_A2 | Down | -0.0741194920 |
| GSE28863_A3 | Up | 0.2233518508 |
| GSE28863_A4 | Up | 0.0244124007 |
| GSE48662 | Down | -0.2163891289 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-100-5p | MIMAT0000098 | MIRT048418 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
