HCSGD entry for TNIP2
1. General information
| Official gene symbol | TNIP2 |
|---|---|
| Entrez ID | 79155 |
| Gene full name | TNFAIP3 interacting protein 2 |
| Other gene symbols | ABIN2 FLIP1 KLIP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0006954 | Inflammatory response | IEA | biological_process |
| GO:0007249 | I-kappaB kinase/NF-kappaB signaling | IEA | biological_process |
| GO:0019901 | Protein kinase binding | IDA | molecular_function |
| GO:0023035 | CD40 signaling pathway | ISS | biological_process |
| GO:0031593 | Polyubiquitin binding | IDA | molecular_function |
| GO:0034134 | Toll-like receptor 2 signaling pathway | ISS | biological_process |
| GO:0034138 | Toll-like receptor 3 signaling pathway | ISS | biological_process |
| GO:0034162 | Toll-like receptor 9 signaling pathway | ISS | biological_process |
| GO:0043032 | Positive regulation of macrophage activation | ISS | biological_process |
| GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | IDA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0050821 | Protein stabilization | ISS | biological_process |
| GO:0050871 | Positive regulation of B cell activation | ISS | biological_process |
| GO:0070498 | Interleukin-1-mediated signaling pathway | ISS | biological_process |
| GO:0071222 | Cellular response to lipopolysaccharide | ISS | biological_process |
| GO:2000352 | Negative regulation of endothelial cell apoptotic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4107764561 | 0.7357570685 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3420382940 |
| GSE13712_SHEAR | Down | -0.0723407978 |
| GSE13712_STATIC | Up | 0.0692817302 |
| GSE19018 | Down | -0.0913719502 |
| GSE19899_A1 | Down | -0.1418370495 |
| GSE19899_A2 | Up | 0.5595654812 |
| PubMed_21979375_A1 | Up | 0.2690007220 |
| PubMed_21979375_A2 | Up | 0.0928267394 |
| GSE35957 | Down | -0.3397889094 |
| GSE36640 | Down | -0.0020233196 |
| GSE54402 | Up | 0.2158647938 |
| GSE9593 | Down | -0.0107157317 |
| GSE43922 | Up | 0.0460612054 |
| GSE24585 | Down | -0.2155607578 |
| GSE37065 | Down | -0.0644800461 |
| GSE28863_A1 | Down | -0.0539915688 |
| GSE28863_A2 | Down | -0.2201979188 |
| GSE28863_A3 | Up | 0.0744322958 |
| GSE28863_A4 | Up | 0.0672774712 |
| GSE48662 | Up | 0.3126040944 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-218-5p | MIMAT0000275 | MIRT024247 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030507 | Microarray | Functional MTI (Weak) | 19748357 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
