HCSGD entry for ALG12
1. General information
| Official gene symbol | ALG12 |
|---|---|
| Entrez ID | 79087 |
| Gene full name | ALG12, alpha-1,6-mannosyltransferase |
| Other gene symbols | CDG1G ECM39 PP14673 hALG12 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000009 | Alpha-1,6-mannosyltransferase activity | IC | molecular_function |
| GO:0005783 | Endoplasmic reticulum | NAS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006457 | Protein folding | NAS | biological_process |
| GO:0006487 | Protein N-linked glycosylation | IGI | biological_process |
| GO:0006488 | Dolichol-linked oligosaccharide biosynthetic process | IDA TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016757 | Transferase activity, transferring glycosyl groups | IEA | molecular_function |
| GO:0018279 | Protein N-linked glycosylation via asparagine | TAS | biological_process |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0052917 | Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity | IEA | molecular_function |
| GO:0097502 | Mannosylation | IC | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3182074959 | 0.7012691957 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0145305600 |
| GSE13712_SHEAR | Down | -0.2475791477 |
| GSE13712_STATIC | Down | -0.2258183764 |
| GSE19018 | Up | 0.2175530455 |
| GSE19899_A1 | Down | -0.1598821545 |
| GSE19899_A2 | Up | 0.4348473296 |
| PubMed_21979375_A1 | Up | 0.2515587680 |
| PubMed_21979375_A2 | Up | 0.4577499728 |
| GSE35957 | Down | -0.4006972393 |
| GSE36640 | Up | 0.0185791871 |
| GSE54402 | Up | 0.1263046133 |
| GSE9593 | Up | 0.0321922421 |
| GSE43922 | Up | 0.0500086082 |
| GSE24585 | Down | -0.0637149687 |
| GSE37065 | Down | -0.1691036204 |
| GSE28863_A1 | Up | 0.2706271068 |
| GSE28863_A2 | Up | 0.4327814304 |
| GSE28863_A3 | Down | -0.0943586507 |
| GSE28863_A4 | Down | -0.1571358214 |
| GSE48662 | Up | 0.2815773181 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017824 | Microarray | Functional MTI (Weak) | 18185580 |
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