HCSGD entry for MLPH
1. General information
| Official gene symbol | MLPH |
|---|---|
| Entrez ID | 79083 |
| Gene full name | melanophilin |
| Other gene symbols | SLAC2-A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001725 | Stress fiber | IEA | cellular_component |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005815 | Microtubule organizing center | IEA | cellular_component |
| GO:0006605 | Protein targeting | IEA | biological_process |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0017137 | Rab GTPase binding | IEA | molecular_function |
| GO:0030318 | Melanocyte differentiation | IEA | biological_process |
| GO:0030864 | Cortical actin cytoskeleton | IEA | cellular_component |
| GO:0031489 | Myosin V binding | IEA | molecular_function |
| GO:0032400 | Melanosome localization | IEA | biological_process |
| GO:0035371 | Microtubule plus-end | IEA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051010 | Microtubule plus-end binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0115150678 | 0.4206386839 | 0.2714286482 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.0089526843 |
| GSE13712_SHEAR | Up | 0.1208842104 |
| GSE13712_STATIC | Up | 0.1504913213 |
| GSE19018 | Up | 0.1946515093 |
| GSE19899_A1 | Up | 1.2947140754 |
| GSE19899_A2 | Up | 0.4892791501 |
| PubMed_21979375_A1 | Up | 0.1531852172 |
| PubMed_21979375_A2 | Up | 0.9583527469 |
| GSE35957 | Down | -3.0948221614 |
| GSE36640 | Down | -1.2208415425 |
| GSE54402 | Up | 1.2904284553 |
| GSE9593 | Up | 1.0324289971 |
| GSE43922 | Up | 0.1902348879 |
| GSE24585 | Down | -0.1135203635 |
| GSE37065 | Up | 0.1666172763 |
| GSE28863_A1 | Down | -0.1554767372 |
| GSE28863_A2 | Up | 0.4698201126 |
| GSE28863_A3 | Down | -0.2510675933 |
| GSE28863_A4 | Up | 0.0255126132 |
| GSE48662 | Down | -0.1839316890 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
