HCSGD entry for FTO
1. General information
| Official gene symbol | FTO |
|---|---|
| Entrez ID | 79068 |
| Gene full name | fat mass and obesity associated |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001659 | Temperature homeostasis | IEA | biological_process |
| GO:0005634 | Nucleus | IEA ISS | cellular_component |
| GO:0006307 | DNA dealkylation involved in DNA repair | IDA | biological_process |
| GO:0008198 | Ferrous iron binding | IDA | molecular_function |
| GO:0010883 | Regulation of lipid storage | IEA | biological_process |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0035515 | Oxidative RNA demethylase activity | IDA IEA | molecular_function |
| GO:0035516 | Oxidative DNA demethylase activity | IDA IEA | molecular_function |
| GO:0035552 | Oxidative single-stranded DNA demethylation | IDA IEA | biological_process |
| GO:0035553 | Oxidative single-stranded RNA demethylation | IDA IEA | biological_process |
| GO:0040014 | Regulation of multicellular organism growth | IEA | biological_process |
| GO:0042245 | RNA repair | IDA IEA | biological_process |
| GO:0043734 | DNA-N1-methyladenine dioxygenase activity | IDA IEA | molecular_function |
| GO:0044065 | Regulation of respiratory system process | IEA | biological_process |
| GO:0060612 | Adipose tissue development | IEA | biological_process |
| GO:0070350 | Regulation of white fat cell proliferation | IEA | biological_process |
| GO:0070989 | Oxidative demethylation | IDA | biological_process |
| GO:0080111 | DNA demethylation | IDA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7142955283 | 0.2336308537 | 0.9999902473 | 0.9311145193 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0115157510 |
| GSE13712_SHEAR | Down | -0.5563506092 |
| GSE13712_STATIC | Down | -0.3840725103 |
| GSE19018 | Down | -0.1848615594 |
| GSE19899_A1 | Down | -0.4515688666 |
| GSE19899_A2 | Up | 0.0164705229 |
| PubMed_21979375_A1 | Up | 0.2909144576 |
| PubMed_21979375_A2 | Up | 1.2007047722 |
| GSE35957 | Up | 0.3080118479 |
| GSE36640 | Up | 0.1141115212 |
| GSE54402 | Down | -0.0348262373 |
| GSE9593 | Down | -0.0041230449 |
| GSE43922 | Down | -0.1779687479 |
| GSE24585 | Down | -0.1733627968 |
| GSE37065 | Down | -0.1735231779 |
| GSE28863_A1 | Up | 0.3241726473 |
| GSE28863_A2 | Down | -0.1054315803 |
| GSE28863_A3 | Down | -0.0810893794 |
| GSE28863_A4 | Up | 0.1246515857 |
| GSE48662 | Down | -0.0028713348 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT052254 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
