HCSGD entry for OTUB2
1. General information
| Official gene symbol | OTUB2 |
|---|---|
| Entrez ID | 78990 |
| Gene full name | OTU domain, ubiquitin aldehyde binding 2 |
| Other gene symbols | C14orf137 OTB2 OTU2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004843 | Ubiquitin-specific protease activity | IDA IMP | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0006520 | Cellular amino acid metabolic process | IDA | biological_process |
| GO:0008242 | Omega peptidase activity | IEA | molecular_function |
| GO:0016579 | Protein deubiquitination | IMP | biological_process |
| GO:0035871 | Protein K11-linked deubiquitination | IDA | biological_process |
| GO:0070536 | Protein K63-linked deubiquitination | IDA | biological_process |
| GO:0071108 | Protein K48-linked deubiquitination | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0006607462 | 0.9751470841 | 0.0740632911 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0512033835 |
| GSE13712_SHEAR | Up | 1.6704699358 |
| GSE13712_STATIC | Up | 0.8641403811 |
| GSE19018 | Up | 0.1885212883 |
| GSE19899_A1 | Up | 0.7013790629 |
| GSE19899_A2 | Up | 3.2006777303 |
| PubMed_21979375_A1 | Up | 2.8263160498 |
| PubMed_21979375_A2 | Up | 2.8909350430 |
| GSE35957 | Up | 0.2614487519 |
| GSE36640 | Up | 0.4384893833 |
| GSE54402 | Up | 0.7882097603 |
| GSE9593 | Up | 0.1740145433 |
| GSE43922 | Up | 2.8713443838 |
| GSE24585 | Up | 0.0134188365 |
| GSE37065 | Down | -0.1211575685 |
| GSE28863_A1 | Down | -0.4315197760 |
| GSE28863_A2 | Down | -0.2972365916 |
| GSE28863_A3 | Up | 0.0218966280 |
| GSE28863_A4 | Down | -0.1034488719 |
| GSE48662 | Up | 0.1628942774 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016886 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024538 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026192 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT045773 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
