HCSGD entry for RAB7A

1. General information

Official gene symbolRAB7A
Entrez ID7879
Gene full nameRAB7A, member RAS oncogene family
Other gene symbolsPRO2706 RAB7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003924GTPase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005525GTP bindingIDA IEAmolecular_function
GO:0005764LysosomeIDAcellular_component
GO:0005765Lysosomal membraneTAScellular_component
GO:0005770Late endosomeIDA IEAcellular_component
GO:0005794Golgi apparatusIDA IEAcellular_component
GO:0006184GTP catabolic processIDA TASbiological_process
GO:0006622Protein targeting to lysosomeIMPbiological_process
GO:0006897EndocytosisTASbiological_process
GO:0007174Epidermal growth factor catabolic processIMPbiological_process
GO:0007264Small GTPase mediated signal transductionIEAbiological_process
GO:0008333Endosome to lysosome transportIMPbiological_process
GO:0015031Protein transportIEA TASbiological_process
GO:0019003GDP bindingIDA IEAmolecular_function
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0030670Phagocytic vesicle membraneIEAcellular_component
GO:0042470MelanosomeIEAcellular_component
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0045022Early endosome to late endosome transportIMPbiological_process
GO:0045335Phagocytic vesicleIDAcellular_component
GO:0045453Bone resorptionIEAbiological_process
GO:0048365Rac GTPase bindingIEAmolecular_function
GO:0090382Phagosome maturationTASbiological_process
GO:0090383Phagosome acidificationIMPbiological_process
GO:0090385Phagosome-lysosome fusionIMPbiological_process
GO:0097208Alveolar lamellar bodyIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07597062040.60125893390.58322003491.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1412702941
GSE13712_SHEARDown-0.0680183681
GSE13712_STATICUp0.0952090071
GSE19018Down-0.0012940895
GSE19899_A1Up0.3492481449
GSE19899_A2Up0.8068558423
PubMed_21979375_A1Up0.4941810037
PubMed_21979375_A2Up0.3255449010
GSE35957Up0.2234723687
GSE36640Up0.3237953313
GSE54402Up0.2878691337
GSE9593Up0.2447848454
GSE43922Up0.1769641023
GSE24585Up0.0787837627
GSE37065Up0.1760970730
GSE28863_A1Down-0.8363615591
GSE28863_A2Down-0.5034436596
GSE28863_A3Up0.0536492008
GSE28863_A4Down-0.5445787691
GSE48662Up0.3500399614

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Guanosine-5'-DiphosphateDB04315 EXPT01573

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-324-3pMIMAT0000762MIRT042998CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.