HCSGD entry for IL1R2
1. General information
| Official gene symbol | IL1R2 |
|---|---|
| Entrez ID | 7850 |
| Gene full name | interleukin 1 receptor, type II |
| Other gene symbols | CD121b CDw121b IL-1R-2 IL-1RT-2 IL-1RT2 IL1R2c IL1RB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004908 | Interleukin-1 receptor activity | TAS | molecular_function |
| GO:0004910 | Interleukin-1, Type II, blocking receptor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006955 | Immune response | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5835619543 | 0.8998362068 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1402143626 |
| GSE13712_SHEAR | Down | -0.1758050790 |
| GSE13712_STATIC | Down | -0.0612565978 |
| GSE19018 | Up | 0.0721078194 |
| GSE19899_A1 | Up | 0.0032948820 |
| GSE19899_A2 | Up | 0.1535036493 |
| PubMed_21979375_A1 | Up | 0.0313720967 |
| PubMed_21979375_A2 | Up | 0.1408579023 |
| GSE35957 | Up | 0.0738921856 |
| GSE36640 | Up | 0.0453680467 |
| GSE54402 | Up | 0.0155783999 |
| GSE9593 | Down | -0.1056784567 |
| GSE43922 | Up | 0.0338156290 |
| GSE24585 | Up | 0.1489645552 |
| GSE37065 | Up | 0.0117076580 |
| GSE28863_A1 | Down | -0.0751615764 |
| GSE28863_A2 | Down | -0.0044405053 |
| GSE28863_A3 | Up | 0.2555930327 |
| GSE28863_A4 | Up | 0.0825516382 |
| GSE48662 | Down | -0.0368024002 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029779 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
