HCSGD entry for ALMS1
1. General information
| Official gene symbol | ALMS1 |
|---|---|
| Entrez ID | 7840 |
| Gene full name | Alstrom syndrome 1 |
| Other gene symbols | ALSS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000922 | Spindle pole | IEA | cellular_component |
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005814 | Centriole | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005929 | Cilium | IEA | cellular_component |
| GO:0016197 | Endosomal transport | IMP | biological_process |
| GO:0051492 | Regulation of stress fiber assembly | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9844479199 | 0.0040878196 | 0.9999902473 | 0.1302428744 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3899548244 |
| GSE13712_SHEAR | Down | -0.0776100088 |
| GSE13712_STATIC | Down | -0.2598871105 |
| GSE19018 | Down | -0.1026229453 |
| GSE19899_A1 | Down | -0.2375985431 |
| GSE19899_A2 | Down | -0.7797845759 |
| PubMed_21979375_A1 | Down | -0.6983811783 |
| PubMed_21979375_A2 | Down | -0.7376713173 |
| GSE35957 | Down | -0.7222894819 |
| GSE36640 | Down | -1.5370811991 |
| GSE54402 | Up | 0.1116672355 |
| GSE9593 | Down | -0.8110469421 |
| GSE43922 | Down | -0.1654417175 |
| GSE24585 | Down | -0.5616635001 |
| GSE37065 | Up | 0.0572925301 |
| GSE28863_A1 | Up | 0.3376513109 |
| GSE28863_A2 | Up | 0.6985995922 |
| GSE28863_A3 | Down | -0.6335320758 |
| GSE28863_A4 | Down | -0.3906165079 |
| GSE48662 | Down | -0.3207765754 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-197-3p | MIMAT0000227 | MIRT004192 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-375 | MIMAT0000728 | MIRT019997 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT031049 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-99b-3p | MIMAT0004678 | MIRT038525 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049216 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-22-3p | MIMAT0000077 | MIRT050457 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
