HCSGD entry for PXDN
1. General information
Official gene symbol | PXDN |
---|---|
Entrez ID | 7837 |
Gene full name | peroxidasin homolog (Drosophila) |
Other gene symbols | D2S448 D2S448E MG50 PRG2 PXN VPO |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0001960 | Negative regulation of cytokine-mediated signaling pathway | NAS | biological_process |
GO:0004601 | Peroxidase activity | IDA IEA | molecular_function |
GO:0005152 | Interleukin-1 receptor antagonist activity | NAS | molecular_function |
GO:0005201 | Extracellular matrix structural constituent | IDA | molecular_function |
GO:0005578 | Proteinaceous extracellular matrix | IEA | cellular_component |
GO:0005615 | Extracellular space | IDA | cellular_component |
GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
GO:0006955 | Immune response | NAS | biological_process |
GO:0006979 | Response to oxidative stress | IEA | biological_process |
GO:0010469 | Regulation of receptor activity | NAS | biological_process |
GO:0020037 | Heme binding | IDA IEA | molecular_function |
GO:0030198 | Extracellular matrix organization | IDA | biological_process |
GO:0031012 | Extracellular matrix | IDA | cellular_component |
GO:0042744 | Hydrogen peroxide catabolic process | IDA | biological_process |
GO:0046872 | Metal ion binding | IEA | molecular_function |
GO:0055114 | Oxidation-reduction process | IDA | biological_process |
GO:1900116 | Extracellular negative regulation of signal transduction | NAS | biological_process |
GO:2000272 | Negative regulation of receptor activity | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.1048993579 | 0.1352930436 | 0.6729761267 | 0.7095134887 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Down | -0.4594524830 |
GSE13712_SHEAR | Up | 0.1043537295 |
GSE13712_STATIC | Down | -0.0386278670 |
GSE19018 | Up | 0.8966474788 |
GSE19899_A1 | Down | -0.1349633107 |
GSE19899_A2 | Up | 0.0630845114 |
PubMed_21979375_A1 | Down | -0.3207935200 |
PubMed_21979375_A2 | Up | 0.0550572379 |
GSE35957 | Down | -0.4582824654 |
GSE36640 | Up | 0.1811964674 |
GSE54402 | Down | -0.3040734429 |
GSE9593 | Up | 0.4689880848 |
GSE43922 | Up | 0.0142018735 |
GSE24585 | Down | -0.1610796936 |
GSE37065 | Down | -0.6033599818 |
GSE28863_A1 | Up | 1.2030454945 |
GSE28863_A2 | Up | 1.0460246851 |
GSE28863_A3 | Up | 0.2858913868 |
GSE28863_A4 | Down | -0.3423907398 |
GSE48662 | Down | -0.1528857371 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-let-7b-5p | MIMAT0000063 | MIRT001602 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
hsa-miR-29a-3p | MIMAT0000086 | MIRT006551 | Luciferase reporter assay//Western blot | Functional MTI | 20566844 |
hsa-miR-9-5p | MIMAT0000441 | MIRT021390 | Microarray | Functional MTI (Weak) | 17612493 |
hsa-miR-1 | MIMAT0000416 | MIRT023628 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
hsa-miR-1 | MIMAT0000416 | MIRT023628 | Proteomics | Functional MTI (Weak) | 18668040 |
hsa-miR-192-5p | MIMAT0000222 | MIRT026257 | Microarray | Functional MTI (Weak) | 19074876 |
hsa-miR-98-5p | MIMAT0000096 | MIRT027510 | Microarray | Functional MTI (Weak) | 19088304 |
hsa-miR-324-5p | MIMAT0000761 | MIRT043023 | CLASH | Functional MTI (Weak) | 23622248 |
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