HCSGD entry for PTP4A1
1. General information
| Official gene symbol | PTP4A1 |
|---|---|
| Entrez ID | 7803 |
| Gene full name | protein tyrosine phosphatase type IVA, member 1 |
| Other gene symbols | HH72 PRL-1 PRL1 PTP(CAAX1) PTPCAAX1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004725 | Protein tyrosine phosphatase activity | NAS | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005769 | Early endosome | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005819 | Spindle | IEA | cellular_component |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0009898 | Cytoplasmic side of plasma membrane | IDA | cellular_component |
| GO:0016791 | Phosphatase activity | IEA | molecular_function |
| GO:0030335 | Positive regulation of cell migration | IEA | biological_process |
| GO:0035335 | Peptidyl-tyrosine dephosphorylation | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0769716424 | 0.9530278751 | 0.5860487706 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0937173970 |
| GSE13712_SHEAR | Up | 0.1584903147 |
| GSE13712_STATIC | Up | 0.1511875482 |
| GSE19018 | Down | -0.0018781154 |
| GSE19899_A1 | Up | 0.3749058947 |
| GSE19899_A2 | Up | 0.3720179581 |
| PubMed_21979375_A1 | Up | 0.7222574635 |
| PubMed_21979375_A2 | Up | 0.4462713458 |
| GSE35957 | Up | 0.0140903576 |
| GSE36640 | Up | 0.3743267628 |
| GSE54402 | Up | 0.2018650813 |
| GSE9593 | Down | -0.1234964857 |
| GSE43922 | Up | 0.3799019771 |
| GSE24585 | Down | -0.1053826753 |
| GSE37065 | Up | 0.1265014487 |
| GSE28863_A1 | Up | 0.0297168741 |
| GSE28863_A2 | Up | 0.5566867006 |
| GSE28863_A3 | Down | -0.2300962597 |
| GSE28863_A4 | Down | -0.2358873130 |
| GSE48662 | Down | -0.0607093693 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020207 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022499 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028544 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029304 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031146 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-106b-3p | MIMAT0004672 | MIRT038554 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042827 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT044985 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048438 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052393 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | NA | hsa-miR-26b | 20831567 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
