HCSGD entry for SLC30A1
1. General information
| Official gene symbol | SLC30A1 |
|---|---|
| Entrez ID | 7779 |
| Gene full name | solute carrier family 30 (zinc transporter), member 1 |
| Other gene symbols | ZNT1 ZRC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0005385 | Zinc ion transmembrane transporter activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0006829 | Zinc ion transport | ISS | biological_process |
| GO:0006874 | Cellular calcium ion homeostasis | ISS | biological_process |
| GO:0006882 | Cellular zinc ion homeostasis | ISS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019855 | Calcium channel inhibitor activity | ISS | molecular_function |
| GO:0030315 | T-tubule | ISS | cellular_component |
| GO:0046929 | Negative regulation of neurotransmitter secretion | ISS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0070509 | Calcium ion import | IEA | biological_process |
| GO:0070574 | Cadmium ion transmembrane transport | ISS | biological_process |
| GO:0071584 | Negative regulation of zinc ion transmembrane import | ISS | biological_process |
| GO:0071585 | Detoxification of cadmium ion | IEA | biological_process |
| GO:0090281 | Negative regulation of calcium ion import | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0519021656 | 0.3359560351 | 0.4989470051 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1340820822 |
| GSE13712_SHEAR | Up | 0.6682537844 |
| GSE13712_STATIC | Up | 0.6804060661 |
| GSE19018 | Down | -1.0599219277 |
| GSE19899_A1 | Down | -0.0470159614 |
| GSE19899_A2 | Down | -0.0711501635 |
| PubMed_21979375_A1 | Up | 0.5599189551 |
| PubMed_21979375_A2 | Up | 0.3942991983 |
| GSE35957 | Up | 0.9256725922 |
| GSE36640 | Up | 0.6316254510 |
| GSE54402 | Down | -0.4077295174 |
| GSE9593 | Up | 0.2579336556 |
| GSE43922 | Up | 0.2072008420 |
| GSE24585 | Up | 0.0072106209 |
| GSE37065 | Up | 0.1477697109 |
| GSE28863_A1 | Up | 0.1492988937 |
| GSE28863_A2 | Up | 0.5864430888 |
| GSE28863_A3 | Down | -0.7041617128 |
| GSE28863_A4 | Down | -0.2016219381 |
| GSE48662 | Down | -0.2639488985 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001501 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031411 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032247 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039676 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041483 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
