HCSGD entry for ZNF174

1. General information

Official gene symbolZNF174
Entrez ID7727
Gene full namezinc finger protein 174
Other gene symbolsZSCAN8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDA IEAbiological_process
GO:0000981Sequence-specific DNA binding RNA polymerase II transcription factor activityIBAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIDA IEAmolecular_function
GO:0005634NucleusIDA IEA NAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIBAbiological_process
GO:0015629Actin cytoskeletonIDAcellular_component
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0044212Transcription regulatory region DNA bindingIDAmolecular_function
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.66758182440.22777412710.99999024730.9185296154

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0629472564
GSE13712_SHEARDown-0.1971037952
GSE13712_STATICDown-0.1167306633
GSE19018Down-0.0706490746
GSE19899_A1Down-0.0077910103
GSE19899_A2Up0.3112338618
PubMed_21979375_A1Up0.5972589427
PubMed_21979375_A2Up0.2281616114
GSE35957Up0.0780632490
GSE36640Up0.3600863738
GSE54402Up0.0741960411
GSE9593Up0.0530683127
GSE43922Down-0.0015691424
GSE24585Down-0.2879074406
GSE37065Down-0.0082565440
GSE28863_A1Down-0.0353681719
GSE28863_A2Down-0.3300855131
GSE28863_A3Down-1.0237099367
GSE28863_A4Up0.0493559470
GSE48662Down-0.1110212618

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-877-5pMIMAT0004949MIRT037309CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049596CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.